BDBM205431 (6S+2S)-PEG1 (7)
SMILES COC(=O)C[C@@H]1N=C(c2c(C)c(sc2-n2c(C)nnc12)C(=O)NCCOCCNC(=O)C[C@@H]1N=C(c2c(C)c(C)sc2-n2c(C)nnc12)c1ccc(Cl)cc1)c1ccc(Cl)cc1
InChI Key InChIKey=FZWPGKYEENZFAU-CONSDPRKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 205431
Affinity DataKd: 16.7nMpH: 7.4Assay Description:ITC experiments were carried out on anAuto-ITC200 titration microcalorimeter (Malvern Instruments). All experimentswere carried out at 25 °C while st...More data for this Ligand-Target Pair
Affinity DataIC50: 0.758nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150...More data for this Ligand-Target Pair
Activity Spreadsheet -- ITC Data from BindingDB
Found 1 hit for monomerid = 205431
ITC DataΔG°: -10.6kcal/mole −TΔS°: -0.733kcal/mole ΔH°: -9.88kcal/mole logk: 6.11E+7
T: 25.00°C
T: 25.00°C